Ovalocytes

Protocol

Ovalocytes

Observation

The ovalocyte is an elliptical red blood cell that is shaped like an egg (oval shaped). It is also called an elliptocyte.

Explanation

Ovalocytes are most abundant in hereditary elliptocytosis, in which the majority of the cells are ellipitical. Ovalocytes are seen in normal persons’ blood, but number less that 10 percent of the cells. They are more common, however, in iron deficiency anemia, myelofibrosis with myeloid metaplasia, megaloblastic anemias, and sickle cell anemia. In some studies it was determined that B12 deficiencies contributed to the instability of the abnormal membrane of the red blood cell.